Product Name Alvimopan
CAS Number 156053-89-3
Formula C25H32N2O4
Molar Mass 420.53 g/mol
Pub Chem CID 5281087
Drug Bank DB01302
Chem Spider 4445785
Bioavailability 6%
Protein Binding 79%
Metabolism Hepatic (CYP3A4)
Elimination Halflife 10 hours
FAQ
What is Alvimopan and how does it work?

Alvimopan is a medication used to help restore normal bowel function after surgery. It works by blocking certain receptors in the intestines that can slow down bowel movements. This helps to reduce the risk of postoperative ileus, a condition where the intestines stop working properly after surgery.

Who can benefit from taking Alvimopan?

Alvimopan is typically prescribed for patients who are undergoing major abdominal surgeries, such as bowel resections or surgeries to treat colon cancer. It is especially beneficial for patients who are at a higher risk of developing postoperative ileus, such as elderly patients or those with a history of bowel motility disorders.

How is Alvimopan taken and what are the common side effects?

Alvimopan is usually taken orally, either with or without food, as directed by a healthcare provider. Common side effects may include nausea, vomiting, diarrhea, abdominal pain, or headaches. It is important to inform your healthcare provider if you experience any severe or persistent side effects while taking Alvimopan.

Are there any precautions or contraindications to taking Alvimopan?

Alvimopan should not be taken by patients who have a history of bowel obstruction, perforation, or severe gastrointestinal conditions. It is also not recommended for patients with severe liver or kidney disease. Before starting Alvimopan, it is important to inform your healthcare provider of any medical conditions you have or medications you are taking to ensure it is safe for you.

How long should Alvimopan be taken for and when can its effects be noticed?

Alvimopan is typically taken for a short duration, usually starting before surgery and continuing for up to 7 days afterward. The effects of Alvimopan can usually be noticed within a few days, as it helps to restore bowel function and reduce the risk of postoperative ileus. It is important to follow the dosing instructions provided by your healthcare provider for the best results.
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