Product Name Dalbavancin Hydrochloride
CAS Number 171500-79-1
Formula C88H100Cl2N10O28
Molar Mass 1818.581 g/mol
Pub Chem CID 46771989
Drug Bank DB12080
Chem Spider 34942956
Bioavailability Not Available
Protein Binding 93%
Metabolism Hepatic
Elimination Halflife 346 hours
FAQ
What is Dalbavancin Hydrochloride and how does it work?

Dalbavancin Hydrochloride is a long-acting lipoglycopeptide antibiotic that is used to treat acute bacterial skin and skin structure infections. It works by inhibiting cell wall synthesis in susceptible gram-positive bacteria, leading to their death.

How is Dalbavancin Hydrochloride different from other antibiotics?

Dalbavancin Hydrochloride has a unique mechanism of action compared to other antibiotics, making it effective against a wide range of gram-positive bacteria. Additionally, its long half-life allows for once-weekly dosing, which can improve patient compliance and reduce the risk of developing resistance.

What are the common side effects of Dalbavancin Hydrochloride?

Common side effects of Dalbavancin Hydrochloride include nausea, headache, diarrhea, and constipation. In some cases, patients may experience more serious side effects such as allergic reactions, liver toxicity, or Clostridium difficile-associated diarrhea. It is important to consult with a healthcare provider if any adverse reactions occur.

How is Dalbavancin Hydrochloride dosed and administered?

Dalbavancin Hydrochloride is typically dosed as a single 1500 mg infusion over a 30-minute period. It is important to administer the medication according to the prescribed dosing regimen to ensure optimal efficacy. Additionally, healthcare providers should monitor patients for any signs of infusion-related reactions during administration.

Is Dalbavancin Hydrochloride appropriate for all patients with bacterial skin infections?

Dalbavancin Hydrochloride is approved for use in adults with acute bacterial skin and skin structure infections caused by susceptible organisms. However, it is important to consider individual patient factors such as allergies, drug interactions, and underlying medical conditions before prescribing Dalbavancin Hydrochloride. Healthcare providers should assess each patient's specific situation to determine the most appropriate treatment option.
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