Product Name Lurbinectedin
CAS Number 497871-47-3
Formula C41H57N5O7
Molar Mass 715.93 g/mol
Pub Chem CID 11791885
Drug Bank DB11731
Chem Spider 9961918
Bioavailability 85%
Protein Binding 97%
Metabolism Mainly hepatic (CYP3A4)
Elimination Halflife 3 to 5 hours
FAQ
What is Lurbinectedin and how does it work as a cancer treatment?

Lurbinectedin is a novel anticancer agent that works by inhibiting the growth of tumor cells through a unique mechanism of action. It targets and binds to specific proteins involved in DNA repair processes within cancer cells, leading to cell death and tumor regression.

How is Lurbinectedin administered to patients and what are the common side effects associated with its use?

Lurbinectedin is administered intravenously, typically in a hospital or clinical setting by healthcare professionals trained in chemotherapy administration. Common side effects of Lurbinectedin may include nausea, fatigue, decreased appetite, and low blood cell counts.

What types of cancer is Lurbinectedin approved to treat, and what stage of the disease is it typically used in?

Lurbinectedin is currently approved for the treatment of metastatic small cell lung cancer (SCLC) in patients who have previously received platinum-based chemotherapy. It is indicated for use in the late stages of the disease when other treatment options have been exhausted.

What are the potential benefits of Lurbinectedin treatment for patients with metastatic small cell lung cancer?

For patients with metastatic small cell lung cancer, Lurbinectedin offers the potential for tumor shrinkage, prolonged progression-free survival, and improved quality of life. It may provide a new treatment option for patients who have not responded to conventional therapies.

Are there any ongoing clinical trials or research studies investigating the use of Lurbinectedin in other types of cancer or treatment settings?

Yes, there are ongoing clinical trials and research studies exploring the potential of Lurbinectedin in other types of cancer, including solid tumors such as ovarian and breast cancer. Researchers are also investigating its use in combination with other drugs to determine its efficacy in different treatment settings.
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