Product Name Mertansine
CAS Number 139504-50-0
Formula C39H67N5O7S
Molar Mass 747.06 g/mol
Pub Chem CID 115976
Drug Bank DB13381
Chem Spider 10313878
Bioavailability Unknown
Protein Binding Unknown
Metabolism Unknown
Elimination Halflife Unknown
FAQ
What is Mertansine?

Mertansine is a potent cytotoxic agent that has shown promise in the treatment of various types of cancer. It is a highly targeted drug that works by binding to specific proteins on the surface of cancer cells, delivering a toxic payload directly to the cancer cells while minimizing harm to healthy cells.

How does Mertansine work?

Mertansine works by binding to a protein called tubulin, which is involved in cell division. Once bound to tubulin, Mertansine disrupts the normal function of the protein, preventing cancer cells from dividing and growing. In addition, Mertansine also triggers apoptosis, or programmed cell death, in cancer cells, further inhibiting their growth.

What types of cancer can Mertansine treat?

Mertansine has shown effectiveness in the treatment of various types of cancer, including breast cancer, lung cancer, and certain types of leukemia. It is particularly effective in cancers that overexpress specific proteins that Mertansine can target. Clinical trials are ongoing to explore the potential of Mertansine in the treatment of other types of cancer as well.

Are there any side effects associated with Mertansine?

Like all cancer treatments, Mertansine can cause side effects. Some common side effects of Mertansine include nausea, fatigue, and hair loss. More serious side effects, such as liver toxicity and peripheral neuropathy, can occur in some patients. It is important for patients to discuss potential side effects with their healthcare providers before starting treatment with Mertansine.

How is Mertansine administered?

Mertansine is typically administered intravenously, either as a single agent or in combination with other cancer treatments. The dosage and frequency of treatment with Mertansine will vary depending on the type and stage of cancer being treated, as well as the overall health of the patient. Patients should work closely with their healthcare providers to develop a treatment plan that is best suited to their individual needs.
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