Product Name Obeticholic acid
CAS Number 459789-99-2
Formula C26H44O4
Molar Mass 420.63 g/mol
Pub Chem CID 11303938
Drug Bank DB06438
Chem Spider 9465248
Bioavailability 50%
Protein Binding 99%
Metabolism Hepatic (mostly via oxidation and conjugation)
Elimination Halflife Approximately 6 days
FAQ
What is Obeticholic acid?
Obeticholic acid is a prescription medicine used to treat primary biliary cholangitis (PBC) in adults. PBC is a chronic liver disease that causes inflammation and destruction of the bile ducts in the liver.

How does Obeticholic acid work?
Obeticholic acid works by reducing the production of bile acids in the liver, which helps to decrease the buildup of bile acids in the liver and slow down the progression of PBC.

What are the common side effects of Obeticholic acid?
The most common side effects of Obeticholic acid include itching, fatigue, abdominal pain, and joint pain. Some people may also experience nausea, diarrhea, or skin rash while taking this medication.

Who should not take Obeticholic acid?
Obeticholic acid may not be suitable for everyone. People with certain liver or kidney problems, a history of gallbladder disease, or allergic reactions to Obeticholic acid should not take this medication. It is important to talk to your doctor before starting treatment with Obeticholic acid to determine if it is safe for you.

How should Obeticholic acid be taken?
Obeticholic acid should be taken exactly as prescribed by your doctor. It is usually taken once daily with or without food. Do not stop taking Obeticholic acid without talking to your doctor first, as stopping suddenly can cause a worsening of your condition.
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