Product Name SGA Saxagliptin
CAS Number 361442-00-4
Formula C18H25N3O2
Molar Mass 315.41 g/mol
Pub Chem CID 11243969
Drug Bank DB06335
Chem Spider 9420709
Bioavailability 64%
Protein Binding 99%
Metabolism Hepatic (primarily via CYP3A4/5)
Elimination Halflife 2.5 hours
FAQ
What is Saxagliptin and how does it work in the body?

Saxagliptin is a medication used to treat type 2 diabetes. It belongs to a class of drugs known as dipeptidyl peptidase-4 (DPP-4) inhibitors. Saxagliptin works by increasing the levels of incretin hormones in the body, which in turn helps regulate blood sugar levels. By inhibiting the DPP-4 enzyme, saxagliptin prolongs the activity of incretin hormones such as GLP-1, which stimulate the release of insulin and reduce the production of glucagon.

How is Saxagliptin taken and what are the common side effects?

Saxagliptin is typically taken once daily, with or without food. It should be taken exactly as prescribed by your healthcare provider. Common side effects of saxagliptin may include upper respiratory tract infection, headache, urinary tract infection, and nasopharyngitis. It is important to consult with your doctor if you experience any side effects while taking saxagliptin.

Who can benefit from taking Saxagliptin and are there any contraindications?

Saxagliptin is recommended for individuals with type 2 diabetes who need help in regulating their blood sugar levels. It can be used alone or in combination with other antidiabetic medications. However, saxagliptin is not recommended for individuals with type 1 diabetes or diabetic ketoacidosis. It is also contraindicated in patients with a history of hypersensitivity to saxagliptin or any of its components.

Are there any drug interactions to be aware of while taking Saxagliptin?

Saxagliptin may interact with other medications, including insulin or sulfonylureas. It is important to inform your healthcare provider about all the medications you are currently taking, including prescription, over-the-counter, and herbal supplements. Your doctor may need to adjust your dosage or monitor you more closely if you are taking saxagliptin with certain drugs.

What are the long-term benefits of taking Saxagliptin for managing type 2 diabetes?

Taking saxagliptin as prescribed by your healthcare provider can help improve glycemic control in individuals with type 2 diabetes. By regulating blood sugar levels, saxagliptin can help reduce the risk of complications associated with diabetes, such as heart disease, kidney damage, and nerve damage. It is important to maintain a healthy lifestyle, including a balanced diet and regular exercise, in combination with taking saxagliptin to maximize its benefits for managing type 2 diabetes.
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