What is Tenofovir alafenamide (TAF) and how does it work?

TAF is a medication used to treat HIV infection in adults and children. It belongs to a class of drugs known as nucleoside reverse transcriptase inhibitors (NRTIs). TAF works by blocking the action of reverse transcriptase, an enzyme that HIV needs to replicate itself.

How is TAF different from other medications used to treat HIV?

TAF is a newer formulation of tenofovir that is more potent and has a lower risk of side effects compared to the older formulation, tenofovir disoproxil fumarate (TDF). TAF can be taken at a lower dose, which reduces the risk of kidney and bone toxicity associated with TDF.

What are the common side effects of TAF?

Some common side effects of TAF include nausea, diarrhea, headache, and fatigue. These side effects are usually mild and go away on their own. However, in some cases, TAF can cause more serious side effects such as liver problems and a buildup of lactic acid in the blood.

How should TAF be taken?

TAF should be taken exactly as prescribed by your healthcare provider. It is usually taken once daily with or without food. It is important not to miss any doses of TAF, as this can lead to the development of drug-resistant HIV strains.

Is TAF safe to use during pregnancy?

TAF may be used during pregnancy if the potential benefits outweigh the risks. Pregnant women with HIV should consult with their healthcare provider to determine the best treatment option for their individual situation. It is important to continue taking TAF as prescribed during pregnancy to prevent the transmission of HIV to the baby.