Product Name DM1-SMCC N2'-deacetyl-N2'-[3-[[1-[[4-[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]cyclohexyl]methyl]-2,5-dioxo-3-pyrrolidinyl]thio]-1-oxopropyl]-maytansine
CAS Number 1228105-51-8
Formula C45H62N4O12S2
Molar Mass 906.151 g/mol
Pub Chem CID 46782478
Drug Bank N/A
Chem Spider 32793660
Bioavailability N/A
Protein Binding N/A
Metabolism N/A
Elimination Halflife N/A
FAQ
What is DM1-SMCC N2'-deacetyl-N2'-[3-[[1-[[4-[[2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]cyclohexyl)methyl]-2,5-dioxo-3-pyrrolidinyl]thio]-1-oxopropyl]-maytansine?

DM1-SMCC N2'-deacetyl-N2'-[3-[[1-[[4-[[2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]cyclohexyl)methyl]-2,5-dioxo-3-pyrrolidinyl]thio]-1-oxopropyl]-maytansine is a potent cytotoxic anticancer agent. It belongs to the maytansinoid family and is commonly used in antibody-drug conjugates for targeted cancer therapy.

How does DM1-SMCC N2'-deacetyl-N2'-[3-[[1-[[4-[[2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]cyclohexyl)methyl]-2,5-dioxo-3-pyrrolidinyl]thio]-1-oxopropyl]-maytansine work?

DM1-SMCC N2'-deacetyl-N2'-[3-[[1-[[4-[[2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]cyclohexyl)methyl]-2,5-dioxo-3-pyrrolidinyl]thio]-1-oxopropyl]-maytansine works by binding to microtubules in cancer cells and disrupting their normal function, ultimately leading to cell death. By conjugating this compound to antibodies that target specific cancer cell surface proteins, it enables precise delivery of the cytotoxic payload to cancer cells while sparing healthy cells.

What are the potential benefits of using DM1-SMCC N2'-deacetyl-N2'-[3-[[1-[[4-[[2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]cyclohexyl)methyl]-2,5-dioxo-3-pyrrolidinyl]thio]-1-oxopropyl]-maytansine in cancer therapy?

The use of DM1-SMCC N2'-deacetyl-N2'-[3-[[1-[[4-[[2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]cyclohexyl)methyl]-2,5-dioxo-3-pyrrolidinyl]thio]-1-oxopropyl]-maytansine in cancer therapy offers several potential benefits, including enhanced efficacy due to its potent cytotoxic activity, targeted delivery to cancer cells resulting in reduced toxicity to healthy tissues, and the ability to overcome resistance mechanisms commonly seen with traditional chemotherapy drugs.

Are there any side effects associated with DM1-SMCC N2'-deacetyl-N2'-[3-[[1-[[4-[[2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]cyclohexyl)methyl]-2,5-dioxo-3-pyrrolidinyl]thio]-1-oxopropyl]-maytansine?

Like any medication, DM1-SMCC N2'-deacetyl-N2'-[3-[[1-[[4-[[2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]cyclohexyl)methyl]-2,5-dioxo-3-pyrrolidinyl]thio]-1-oxopropyl]-maytansine can cause side effects. Common side effects may include nausea, vomiting, fatigue, and decreased blood cell counts. It is important to discuss potential side effects with your healthcare provider before starting treatment with this medication.

How can I access DM1-SMCC N2'-deacetyl-N2'-[3-[[1-[[4-[[2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]cyclohexyl)methyl]-2,5-dioxo-3-pyrrolidinyl]thio]-1-oxopropyl]-maytansine for cancer therapy?

DM1-SMCC N2'-deacetyl-N2'-[3-[[1-[[4-[[2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]cyclohexyl)methyl]-2,5-dioxo-3-pyrrolidinyl]thio]-1-oxopropyl]-maytansine is typically available through healthcare providers or specialized pharmacies that dispense antibody-drug conjugates for cancer therapy. Your oncologist or healthcare team will guide you on the appropriate steps to access and receive treatment with DM1-SMCC N2'-deacetyl-N2'-[3-[[1-[[4-[[2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]cyclohexyl)methyl]-2,5-dioxo-3-pyrrolidinyl]thio]-1-oxopropyl]-maytansine.
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